Academic Catalog

Pathobiology (PATH)

PATH 1000.  Biomedical Issues in Pathobiology.  (2 Credits)  
This introductory course focuses on current global issues of health and disease to describe fundamental topics in pathobiology. Global biomedical concerns regarding infectious diseases, population, cancer, biotechnology and environmental health will be addressed. Course content will provide examples of the impact of veterinary and human pathology on world health issues. Formerly offered as PVS 1000.
  
PATH 1100E.  One Health: People, Animals, Plants, and the Environment.  (3 Credits)  
Exploration of health concepts and ecosystems where people, animals, plants, and the environment interconnect and impact each other. CA 3.
  
Skill Codes: COMP: Environmental Literacy  
Content Areas: CA3: Science & Technology  
Topics of Inquiry: TOI4: Environmental Literacy, TOI6: Science & Empirical Inq  
PATH 1201.  Exploring Careers in Pathobiology.  (2 Credits)  
Exposure to the Pathobiology major and careers in Pathobiology through interactions with professionals in relevant careers, training in basic laboratory safety and research compliance, and development of a personalized career journal.
  
PATH 1202.  Fundamental Biomedical Laboratory Techniques.  (2 Credits)  
Hands-on, basic biomedical research laboratory techniques with an emphasis on chemical and biological safety, as well as laboratory proficiency.
  
PATH 2095.  Special Topics.  (1-6 Credits)  
Credits, prerequisites and hours as determined by the Senate Curricula and Course Committee. Formerly offered as PVS 2095.
Prerequisites and recommended preparation vary.  
May be repeated for credit  
PATH 2100.  Anatomy and Physiology of Animals.  (4 Credits)  
A study of the anatomy and physiology of animals with reference to pathological changes of the component parts of the body. Formerly offered as PVS 2100.
BIOL 1107 or equivalent.  
  
PATH 2200.  Modern Biomedical Laboratory Techniques.  (3 Credits)  
Comprehensive project-based laboratory course utilizing a variety of modern biomedical techniques to identify an unknown pathogen and express antigens for vaccine and diagnostic assay development. Topics covered include next-generation sequencing, CRISPR gene editing, mRNA technology, gene cloning and expression, protein purification and analysis, immunoassay, and reverse transcription quantitative PCR development.
BIOL 1107 or equivalent. Recommended preparation: PATH 1202.  
  
PATH 2301.  Health and Disease Management of Animals.  (3 Credits)  
Designed for students who plan to own and work with domestic animals. Its purpose is to develop student competence in disease management and to foster an intelligent working relationship with their veterinarian. The course will cover a systematic study of infectious and noninfectious diseases of domestic animals from the standpoint of economy and public health. Formerly offered as PVS 2301.
  
PATH 2710.  Medical Microbiology: Bacteria and Fungi.  (4 Credits)  
Fundamental biology of pathogenic bacteria and fungi including host-pathogen interactions and microbiological laboratory techniques.
BIOL 1107 or equivalent.  
  
PATH 2720.  Medical Microbiology: Viruses and Parasites.  (4 Credits)  
Fundamental biology of medically relevant viruses and parasites including host-pathogen interactions and microbiological laboratory techniques.
BIOL 1107 or equivalent.  
  
PATH 2800.  Medical Cell Biology.  (3 Credits)  
Foundations of cellular structures and molecular basis of disease, from essential components of eukaryotic cells to cellular responses to injury and disease.
BIOL 1107 or equivalent.  
  
PATH 3093.  Foreign Studies in Pathobiology.  (1-15 Credits)  
Special topics taken in a foreign study program. Formerly offered as PVS 3093.
May be repeated for a total of 15 credits  
PATH 3094W.  Seminar.  (2 Credits)  
Majors may take this course in each semester of the senior year. Formerly offered as PVS 3094W.
ENGL 1007 or 1010 or 1011.  
May be repeated for credit  
Skill Codes: COMP: Writing Competency  
PATH 3095.  Special Topics.  (1-6 Credits)  
Topics and credits to be published prior to the registration period preceding the semester offerings. Formerly offered as PVS 3095.
May be repeated for credit  
PATH 3099.  Independent Study.  (1-6 Credits)  
Special problems in connection with departmental research programs and diagnostic procedures for diseases of animals. Some suggested topics are histopathologic laboratory procedures, clinical hematology, diagnostic bacteriology, diagnostic parasitology. Formerly offered as PVS 3099.
May be repeated for credit  
PATH 3100.  Histologic Structure and Function.  (4 Credits)  
Designed for students in biologic, paramedical and animal sciences; its purpose is to integrate histologic and cellular structure with function, utilizing human tissues and those from other vertebrates. Formerly offered as PVS 3100.
Open to juniors or higher; open only with consent of instructor. Recommended preparation: PATH 2100 or PNB 2264-2265 or PNB 2274-2275 or an equivalent course in vertebrate anatomy and physiology.  
  
PATH 3201.  Principles of Animal Virology.  (3 Credits)  
Structure and classification of viruses, cultivation and multiplication, pathogenesis and epidemiology of viral infections, host response, oncogenic viruses, immunization against, and laboratory diagnosis of viral diseases. Formerly offered as PVS 3201.
Open to juniors or higher.  
  
PATH 3201W.  Principles of Animal Virology.  (3 Credits)  
Structure and classification of viruses, cultivation and multiplication, pathogenesis and epidemiology of viral infections, host response, oncogenic viruses, immunization against, and laboratory diagnosis of viral diseases. Formerly offered as PVS 3201W.
ENGL 1007 or 1010 or 1011 or 2011; open to juniors or higher.  
  
Skill Codes: COMP: Writing Competency  
PATH 3341.  Pathobiology of the Avian Species.  (3 Credits)  
A systematic study of metabolic, nutritional, genetic, and infectious diseases of commercial poultry, avian wildlife, and caged pet birds. Emphasis is placed upon diagnosis and disease prevention. For each system of the body, pertinent anatomy, physiology, histology, pathology, and histopathology will be discussed. Formerly offered as PVS 3341.
Open to juniors or higher.  
  
PATH 3401.  Immunobiology.  (3 Credits)  
Principles of basic and clinical immunobiology; phylogeny and ontogeny of the immune response, characteristics of the immune response, cellular and humoral immunity; central and peripheral lymphoid tissues; mechanisms of immunologic injury and immunologic diseases; comparative and veterinary immunology; transplantation and tumor immunology.
BIOL 1107. Recommended preparation: Previous coursework in Cell Biology.  
  
PATH 3501.  Diagnostic Techniques for the Biomedical Sciences.  (2 Credits)  
(Also offered as AH 3501.) Theoretical basis and practical exposure to modern laboratory methods used in the biomedical sciences for disease diagnosis. Formerly offered as PVS 3501.
MCB 3414; open to juniors or higher; open to Agricultural Biotechnology minors. Recommended preparation: MCB 2000.  
  
PATH 3700.  Emerging Infectious Diseases and Pandemics.  (3 Credits)  
Mechanisms of emergence that different pathogens have used to cause disease in new hosts. Formerly offered as PVS 3700.
  
PATH 3810.  Systems Pathophysiology I.  (3 Credits)  
Organ-based study of human and animal diseases. Use of gross, microscopic, and physiologic evidence to diagnose disease. Topics covered include respiratory, cardiovascular, hematopoietic, lymphoid, musculoskeletal, and urinary systems.
Recommended preparation: PATH 2800 or equivalent.  
  
PATH 3820.  Systems Pathophysiology II.  (3 Credits)  
Organ-based study of human and animal diseases. Use of gross, microscopic, and physiologic evidence to diagnose disease. Topics covered include central nervous, skin, hepatobiliary, endocrine, and digestive systems.
Recommended preparation: PATH 2800 or equivalent.  
  
PATH 4000.  Bioinformatics in Molecular Epidemiology of Infectious Diseases.  (3 Credits)  
Basic concepts and terminologies in bioinformatics and infectious disease epidemiology. Hands-on, practical experiences in sequence analysis: database, alignment, phylogenetic analysis, and visualization of data. Formerly offered as PVS 4000.
  
PATH 4197W.  Pathobiology Honors Thesis.  (3 Credits)  
Writing of Honors thesis based on an independent research project in Pathobiology.
ENGL 1007 or 1010 or 1011; open only to Honors students; instructor consent required.  
  
Grading Basis: Honors Credit  
Skill Codes: COMP: Writing Competency  
PATH 4203.  Principles of Antibacterial Development.  (3 Credits)  
Designed to cover important concepts and pioneering strategies currently being used to develop novel antibacterials. Formerly offered as PVS 4203.
MCB 2610, or an equivalent course in general microbiology or bacteriology with consent of the instructor. Open to juniors or higher.  
  
PATH 4230.  Vaccines and Immunotherapeutics.  (3 Credits)  
Students develop an understanding of approaches for scientists and engineers to use the immune system to combat infectious and chronic diseases. Both traditional and modern molecular approaches to vaccine and immunotherapy design will be discussed. Students will gain an appreciation for the transition from basic research to practical applications.
PATH 3401 or an equivalent course in immunology.  
  
PATH 4300.  Principles of Pathobiology.  (3 Credits)  
The body's response to chemical, physical, and microbial injuries including the functional and morphologic alterations in disease of the major organ systems. Formerly offered as PVS 4300.
PATH 2100 or PNB 2264-2265 or PNB 2274-2275 or an equivalent course in vertebrate anatomy and physiology; open to juniors or higher. Recommended preparation: PATH 3100 or equivalent course in histology or cell biology.