Head of Department: Professor Joseph J. Loturco
Department Office: Room 125A, Torrey Life Science Building
One credit. Open to first-year students, others with consent of instructor. Students taking this course will be assigned a final grade of S (satisfactory) or U (unsatisfactory).
An introduction for declared and prospective Physiology and Neurobiology majors. Introduces key discoveries, current research areas, and technological innovations in physiology and neurobiology, and develops familiarity with the PNB department.
Introduction to research in computational biology through lectures, computer lab exercises, and mentored research projects. Topics include gene and genome structure, gene regulation, mechanisms of inheritance, biological databases, sequence alignment, motif finding, human genetics, forensic genetics, stem cell development, comparative genomics, early evolution, and modeling complex systems. CA 3.
Physiological mechanisms and regulation in vertebrate animals.
Four credits each semester. Three class periods and one 3-hour laboratory. Prerequisite: BIOL 1107, and one of CHEM 1122 or 1124Q or 1127Q. Not open to students who have passed PNB 2274–2275. These courses must be taken in sequence to obtain credit, and may not be counted toward the Biological Sciences or Physiology and Neurobiology majors.
Fundamentals of human anatomy and physiology for students in medical technology, physical therapy, nursing, and education (Sport Science).
Four credits each semester. Three class periods and one 3-hour laboratory. Prerequisite: BIOL 1107, and either CHEM 1124Q or 1127Q. Not open to students who have passed PNB 2264–2265. Must be taken in sequence to obtain credit.
Fundamentals of human physiology and anatomy enhanced through inquiry-based laboratories.
Principles of effective scientific writing focusing on the communication of physiology and neurobiology to lay audiences.
Variable (1 to 4) credits. Hours by arrangement. Prerequisite: Open with consent of department head. May be repeated for a total of up to 6 credits. One credit may be earned for each 42 hours of pre-approved activities up to a maximum of 4 credits. May be applied towards the major with permission of department head subject to the PNB major’s 3-credit research group limitation. Students taking this course will be assigned a final grade of S (satisfactory) or U (unsatisfactory).
Supervised field work at an off-campus research organization or business. Activities that meet objectives consistent with a major in Physiology and Neurobiology must be planned and agreed upon in advance by the job site supervisor, the faculty coordinator and the student.
Three credits. Two class periods. Prerequisite: One 2000-level course in PNB or instructor consent; open to juniors or higher.
Brain functions, from molecular and cellular to overall central nervous system organization. Topics of current scientific interest.
Advanced, in-depth examination of animal comparative physiology.
Anatomy of the human brain and spinal cord; emphasis on the structure and functions of major regions in the central nervous system.
Principles of stem cell biology and the use and applications of stem cells in research and therapy. Emphasis on molecular, cellular and physiological properties of stem cells, mechanisms of differentiation, use of recombinant DNA technology and application of stem cells in disease models.
Two credits. Two class periods. Prerequisite: One 2000-level course in PNB or instructor consent; open to juniors or higher.
Functions of hormones in mammalian physiology emphasizing humans.
Experimental investigations in neurobiology. Emphasis on designing and carrying out independent research projects, and on communicating the results.
Case study of a disease: genetics and inheritance patterns, molecular defects, including transcription and post-transcription defects, physiological defects, therapeutic approaches.
Three credits. Prerequisite: A 2000-level course in PNB or instructor consent; open to juniors or higher.
The evolution of hormonal signaling systems in invertebrates and vertebrates.
Molecular mechanism(s) of hormone action in vertebrates and invertebrates. Molecular and genetic characterization of hormones, receptors, and signal transduction, and hormone actions at the molecular, cellular, and organismal levels. Includes student presentations on selected papers.
First nine weeks. Two credits. Prerequisite: One 2000-level course in PNB or instructor consent; open to juniors or higher. Not open to students who have passed PNB 3276. Recommended preparation: MCB 2000 or 3010.
Various neurotransmitter systems in the brain including anatomy, physiology, cell biology and biochemistry. Neurotransmitters, receptors and transporters at synapses. Synaptic signaling pathways and molecules.
Two credits. Two class periods. Prerequisite: Consent of instructor required.
Introductory grounding and experience for students interested in the healing professions in how patients and families experience illness, and what it’s like to be a professional health provider.
One credit. Weekly 2-hour lecture for ten weeks. May be repeated for credit.
Presentations by Medical and Dental School faculty on basic sciences supporting dental and medical clinical practices. Students taking this course will be assigned a final grade of S (satisfactory) or U (unsatisfactory).
Credits and hours by arrangement. Prerequisite: Open to juniors or higher; consent of Department Head or Key Advisor required, normally to be granted prior to the student’s departure. May count toward the major with consent of Department Head or Key Advisor. May be repeated for credit.
Special topics taken in a foreign study program.
Credits and hours by arrangement. Prerequisite: Open to juniors or higher. May be repeated for credit with a change in topic.
Credits and hours by arrangement. Prerequisites and recommended preparation vary; open to juniors or higher. With a change in content, may be repeated for credit.
Three credits. Prerequisite: Open to juniors or higher. With a change in topic, may be repeated for credit. Prerequisites and recommended preparation vary.
Credits and hours by arrangement. Prerequisite: Open only with consent of instructor and the department honors committee. May be repeated for credit with change in topic.
Designed for the advanced undergraduate student who desires to pursue a special problem as an introduction to independent investigation.
Non-coding RNAs: discovery, major classes, regulatory pathways, physiology, disease, research methodology.
Three credits. Prerequisite: One 2000-level course in PNB, or instructor consent; open to juniors or higher.
Fundamental mechanisms by which water and small molecules are transported across biological membranes. Biophysical and biochemical analysis of transport by diffusion, osmosis, channels, carriers and pumps in health and disease.
Two credits. First nine weeks. Prerequisite: One 2000-level course in PNB, or instructor consent; open to juniors or higher.
Cellular and molecular mechanisms controlling cardiovascular and respiratory function in health and disease.
Cellular and molecular mechanisms supporting the detection of sensory stimuli in vertebrates, invertebrates and other organisms. Detection of chemicals, touch, temperature, pain, sound, light, heat, magnetic fields, and electricity.
Neural mechanisms of stereotyped behavior in vertebrates and invertebrates, emphasizing model systems. Shaping of these systems by environmental requirements and the evolutionary histories of the animals.
Three credits. Hours by arrangement. Prerequisite: Three credits of PNB 3299, which may be taken concurrently; ENGL 1010 or 1011 or 2011; open to juniors or higher; open only with consent of instructor and departmental honors committee. Not limited to honors students.
Special research or independent investigation for advanced undergraduates. Involves research and writing a thesis.
Basic principles of genetics, molecular and cell biology, and physiology as applied to the mechanisms of disease and repair processes in the nervous system. Topics include established concepts and areas of current research on chronic neurodegenerative, synaptic, and demyelinating disorders, acute trauma and cerebrovascular disorders, and plasticity and repair.