Undergraduate Course Directory

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Courses by Subject Area

Click on the links below for a list of courses in that subject area. You may then click “View Classes” to see scheduled classes for individual courses. See the Ratcliffe Hicks Courses page for a list of those courses.

1200. Virus Hunters

4.00 credits

Prerequisites: Not open for credit to students who have passed MCB 1895 when taught as `Virus Hunting Laboratory.'

Grading Basis: Graded

Introduction to the biology of bacterial viruses (phages). Isolation from the environment and characterization of a novel phage for sequencing in MCB 1201. Data from this classroom-based research experience will be shared in a nationwide program fostering discovery-based undergraduate research. May be taken before or after MCB 1201 for students choosing both classes. CA 3-LAB.

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1201. Virus Hunting: Applied Bioinformatics

4.00 credits

Prerequisites: None.

Grading Basis: Graded

Analysis of bacteriophages isolated in MCB 1200. Computational biology approaches including genome assembly, phylogenetic analysis and database searching to characterize gene content and evolutionary relationships. Focus on research methods and approaches, data interpretation, written and oral communication of scientific findings. CA 3-LAB.

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1401. Honors Core: Computational Molecular Biology

Also offered as: BME 1401, CSE 1401, PNB 1401

3.00 credits

Prerequisites: None.

Grading Basis: Honors Credit

Introduction to research in computational biology through lectures, computer lab exercises, and mentored research projects. Topics include gene and genome structure, gene regulation, mechanisms of inheritance, biological databases, sequence alignment, motif finding, human genetics, forensic genetics, stem cell development, comparative genomics, early evolution, and modeling complex systems. CA 3.

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1405. Honors Core: The Genetics Revolution in Contemporary Culture

3.00 credits

Prerequisites: Open only to freshmen and sophomores in the Honors Program.

Grading Basis: Honors Credit

Exploration of the use of genetics concepts in popular culture. Topics include genetic analysis, genetic engineering, cloning and DNA forensics as represented in media including news, film, literature and art. Discussion includes influence on society, attitudes towards science, domestic and foreign policy as well as medical practice and law. CA 3. SM-2/25/08

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1893. Foreign Study

1.00 - 6.00 credits | May be repeated for a total of 6 credits.

Prerequisites: None.

Grading Basis: Graded

Special topics taken in an international study program. May be repeated for credit.

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1895. Special Topics in Molecular and Cell Biology

1.00 - 4.00 credits | May be repeated for a total of 8 credits.

Prerequisites: Prerequisites and recommended preparation vary.

Grading Basis: Graded

Credits and hours by arrangement. With a change in content, may be repeated for credit.

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2000. Introduction to Biochemistry

4.00 credits

Prerequisites: CHEM 2241 or 2444. CHEM 2444 may be taken concurrently. Not open for credit to students who have passed MCB 3010. Repeat restrictions apply. See advising.uconn.edu/repeat-policy for information.

Grading Basis: Graded

The structure, chemistry, and metabolism of carbohydrates, lipids and proteins. Enzyme function and kinetics, energy metabolism, and structure and function of nucleic acids. A survey course for students of agriculture, general biology, medical technology, nursing, and pharmacy. Molecular and Cell Biology majors, biophysics majors, and other students desiring a more intensive introduction or considering advanced course work in biochemistry or molecular biology should take MCB 3010.

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2210. Cell Biology

3.00 credits

Prerequisites: BIOL 1107. Not open for credit to students who have passed MCB 2215, 3211, or 3220.

Grading Basis: Graded

Structural organization of cells and the molecular basis of dynamic cellular processes, with emphasis on eukaryotic cells. Topics include protein targeting, vesicle trafficking, cytoskeleton, cell-cell interactions in tissues, and the molecular basis of related human diseases. Intended to be taken before MCB 2000 or 3010.

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2215. Honors Cell Biology

3.00 credits

Prerequisites: BIOL 1107. Not open to students who have passed MCB 2210.

Grading Basis: Graded

Overview of eukaryotic cell biology for Honors students. Emphasizes primary research literature and in-class discussion.

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2225. Cell Biology Laboratory

4.00 credits

Prerequisites: BIOL 1107 or equivalent; open to honors students, non-honors students with instructor consent.

Grading Basis: Honors Credit

A laboratory experience that will prepare students for thesis research in the biological sciences. Experimental design, quantitative analysis and presentation of data. Topics include cell culture, fluorescence and time-lapse microscopy, DNA transfection, image processing, and flow cytometry. Students will also pursue independent research projects. SM - 9/22/15

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2400. Human Genetics

3.00 credits

Prerequisites: BIOL 1107; not open to students who have passed MCB 2410.

Grading Basis: Graded

Foundational principles of classical genetics and modern genomics with a specific focus on humans. Emphasis on case studies and applications to human genetic diseases.

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2410. Genetics

3.00 credits

Prerequisites: BIOL 1107. Not open to students who have passed MCB 2400. Repeat restrictions apply; see advising.uconn.edu/repeat-policy for information.

Grading Basis: Graded

Foundational principles of classical genetics and modern genomics with a focus on eukaryotic model genetic organisms. Emphasis on molecular mechanisms underlying heredity. Intended for majors in MCB and related disciplines.

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2610. Fundamentals of Microbiology

4.00 credits

Prerequisites: CHEM 2241 or 2443, which may be taken concurrently. Recommended preparation: BIOL 1107. Cannot be taken for credit after MCB 3246, 3617, 3633, 3635, 3636, 3637, 3640, or 4624. Repeat restrictions apply; see advising.uconn.edu/repeat-policy for information.

Grading Basis: Graded

Biology of microorganisms, especially bacteria. Cellular structure, physiology, genetics, and interactions with higher forms of life. Laboratory familiarizes students with methodology of microbiology and aseptic techniques.

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2612. Honors Core: Microbe Hunters - Crowdsourcing Antibiotic Discovery

4.00 credits

Prerequisites: None.

Grading Basis: Graded

Concepts of microbiology taught through the lens of antibiotic resistance. Using environmental samples students actively engage in the hunt for novel antimicrobials. Broader concepts include the meaning of disease, how that meaning has changed over time and the implications of widespread antibiotic resistance for society. CA 3-LAB.

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2893. Foreign Study

1.00 - 5.00 credits | May be repeated for credit.

Prerequisites: None.

Grading Basis: Graded

Special topics taken in an international study program. Consent of Associate Department Head for Undergraduate Research and Education required, normally to be granted before the student's departure.

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3003. Biophysical Chemistry I

3.00 credits

Prerequisites: Prerequisite: MATH 2110Q or 2130Q; PHYS 1402Q, 1502Q, or 1602Q, or instructor permission. Recommended preparation: MCB 2000 or 3010.

Grading Basis: Graded

An introduction to the physical chemistry of biological molecules and systems. Principal topics include biomolecular thermodynamics, kinetics, transport properties, and biomolecular structure.

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3004. Biophysical Chemistry II

3.00 credits

Prerequisites: Prerequisite: MATH 2110Q or 2130Q; PHYS 1402Q, 1502Q, or 1602Q, or instructor consent. Recommended preparation: MCB 2000 or 3010; MCB 3003 or CHEM 3563.

Grading Basis: Graded

The physical chemistry of biological molecules and systems. Emphasis on a statistical framework for understanding biomolecular phenomena. Principal topics will include electrostatics, intermolecular forces, ligand binding, and protein stability and folding.

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3010. Biochemistry

5.00 credits

Prerequisites: CHEM 2444, which may be taken concurrently. Recommended preparation MCB 2210 or 2610. Not open for credit to students who have passed MCB 2000. Repeat restrictions apply. Go to http://www.advising.uconn.edu/repeatpolicy.php for more information.

Grading Basis: Graded

The structure and function of biological macromolecules. The metabolism of carbohydrates, lipids, amino acids, proteins and nucleic acids. The regulation of metabolism and biosynthesis of biological macromolecules. An in-depth introduction intended for students planning to take advanced coursework in biochemistry, biophysics or other areas of molecular biology.

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3011. Human Metabolism and Disease

2.00 credits

Prerequisites: MCB 2000 or 3010 or instructor consent.

Grading Basis: Graded

A thorough analysis of the inter-relationships of metabolic pathways in connection with human health and disease, including inherited metabolic diseases and the role of hormones in metabolic pathways.

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3022W. Human Disease and the Development of Therapeutic Agents

3.00 credits

Prerequisites: ENGL 1010 or 1011 or 2011. Recommended preparation: one 2000 level course in MCB.

Grading Basis: Graded

Molecular basis of human disease and strategies for developing therapeutic treatments. Applications of genetic, cellular, and biochemical information in treating disease states. Especially appropriate for students interested in biomedical research and the health profession.

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3100. Introduction to Translational Research

3.00 credits

Prerequisites: BIOL 1107; open to juniors or higher; open to honors students, others with instructor consent. Recommended preparation: MCB 2000, 2210, 2610 or 3010.

Grading Basis: Honors Credit

Basic science and design of human subject research; participation in clinical, patient-oriented research projects in a hospital setting.

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3189. Clinical Research Laboratory

3.00 credits | May be repeated for credit.

Prerequisites: MCB 3100

Grading Basis: Graded

Participation in a clinical research study at a medical center (transportation to this off-campus site to be arranged by the student). May be repeated for credit.

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3201. Gene Expression

3.00 credits

Prerequisites: Recommended preparation: MCB 2000, 2210, 2400, 2410 or 3010.

Grading Basis: Graded

Basic mechanisms of genetic information transfer in eukaryotic cells from DNA to folded and assembled proteins. Regulation of transcription, translation, DNA replication, and the cell cycle.

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3210. Molecular Endocrinology

Also offered as: PNB 3270

3.00 credits

Prerequisites: BIOL 1107; open to juniors or higher. Recommended preparation: PNB 3262.

Grading Basis: Graded

Molecular mechanism(s) of hormone action in vertebrates and invertebrates. Molecular and genetic characterization of hormones, receptors, and signal transduction, and hormone actions at the molecular, cellular, and organismal levels. Includes student presentations on selected papers.

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3211. Cancer Cell Biology and Genetics

3.00 credits

Prerequisites: MCB 2210. Recommended preparation: MCB 2400 or 2410.

Grading Basis: Graded

Genetics and epigenetics of cancer cells. Cellular signaling and growth control. The role of oncogenes and tumor suppressor genes in regulating cancer cell proliferation and death. DNA damage and repair mechanisms. Carcinogen activation detoxification. General and targeted approaches to cancer therapy.

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3219. Developmental and Regenerative Biology

3.00 credits

Prerequisites: BIOL 1107. Recommended preparation: MCB 2210 and 2400 or 2410 which may be taken concurrently.

Grading Basis: Graded

Fundamental principles that govern animal embryonic development and regeneration with emphasis on the cellular and molecular basis of pattern formation and cell differentiation in a variety of model organisms. Relevance to human development and disease and therapeutic applications will be discussed.

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3220. Developmental Biology Laboratory

4.00 credits

Prerequisites: MCB 2210 and MCB 2400 or 2410. Recommended preparation: MCB 3219.

Grading Basis: Graded

Zebrafish used as an experimental model system to investigate molecular mechanisms of vertebrate development. Self-directed experiments utilize cellular, genetic, pharmacological and microscopic techniques to recreate established findings and pursue new knowledge.

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3246. Virology

3.00 credits

Prerequisites: MCB 2610 and MCB 2210. Recommended preparation: MCB 3201 or 3010.

Grading Basis: Graded

Biological, biochemical, physical, and genetic characteristics of viruses, with an emphasis on molecular and quantitative aspects of virus-cell interactions.

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3400. Human Evolutionary Genomics

3.00 credits

Prerequisites: Prerequisite: MCB 2400 or 2410. Recommended preparation: EEB 2245.

Grading Basis: Graded

Principles of evolutionary genomics and their applications in understanding recent human evolutionary history and the origin and distribution of genetic and phenotypic variation, including disease, within and among human populations.

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3410. Eukaryotic Genomics

3.00 credits

Prerequisites: Prerequisite: MCB 2400 or 2410; open to sophomores or higher.

Grading Basis: Graded

Introduction to the study of eukaryotic genomes. Topics include genome sequence organization and analysis, comparative genomics, structural variants, transposable elements and genome regulation in human health and disease.

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3412. Genetic Engineering and Functional Genomics

3.00 credits

Prerequisites: MCB 2400 or 2410. Recommended preparation: MCB 2000 or 3010.

Grading Basis: Graded

Methods and applications of genetic engineering, including gene manipulation and transfer techniques in prokaryotes and eukaryotes. Emphasis on applications of recombinant DNA technology in the elucidation of gene function. Consideration of recent technological developments in molecular genetics, such as cloning, gene therapy, the patenting and release of genetically engineered organisms, and societal issues related to these developments.

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3413. Concepts of Genetic Analysis

4.00 credits

Prerequisites: MCB 2400 or 2410. Not open for credit to students who have passed MCB 2413.

Grading Basis: Graded

Survey of genetic theory and applications of genetic analysis to model organisms including animals, plants, and microbes.

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3421. Introduction to Molecular Evolution and Bioinformatics

3.00 credits

Prerequisites: Recommended preparation: At least one 2000 level course in MCB.

Grading Basis: Graded

Evolution of biomolecules and application to molecular data analysis and the design of new molecules. Topics include prebiotic chemistry, origin of cells, selfish genes, molecular innovations, data bank searches, alignment of sequence and 3-D protein structures. Course includes lectures, discussions and computer lab exercises.

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3602W. Introduction to Bioinformatic Tools for Microbial Genome Annotation

1.00 credits

Prerequisites: MCB 2000 or 2610 or 3010; ENGL 1010 or 1011 or 2011.

Grading Basis: Graded

Analysis of microbial genome sequences using computational tools to examine metabolic pathways and genetic features as they relate to an organism's lifestyle. Writing assignments utilize information gathered from the relevant scientific literature and students' analyses of genome-derived information.

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3617. Molecular Biology and Genetics of Prokaryotes

4.00 credits

Prerequisites: MCB 2610.

Grading Basis: Graded

Molecular genetics of bacteria, archaebacteria, and their viruses. Transcription and replication of DNA, transformation, transduction, conjugation, genetic mapping, mutagenesis, regulation of gene expression, genome organization.

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3633. Pathogenic Microbiology

4.00 credits

Prerequisites: MCB 2610.

Grading Basis: Graded

Descriptions of infectious diseases caused by bacteria, viruses, and protozoans in relation to the affected human organ systems and discussions of the underlying virulence factors, molecular mechanisms, and epidemiological data. Modern techniques are used in the laboratory to identify and characterize pathogenic bacteria.

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3637. Practical Methods in Microbial Genomics

3.00 credits

Prerequisites: MCB 2610 or instructor consent.

Grading Basis: Graded

Analysis of microbial genomes, including genome assembly, annotation, and comparison. Students will design and perform computational analyses of public domain genomic data. No previous computational experience is expected.

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3841W. Research Literature in Molecular and Cell Biology

3.00 credits | May be repeated for credit.

Prerequisites: ENGL 1010 or 1011 or 2011. Recommended preparation: One 2000 level course in MCB.

Grading Basis: Graded

Discussion of current research in molecular and cell biology. With a change in content, may be repeated for credit.

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3842W. Current Investigations in Cancer Cell Biology

3.00 credits

Prerequisites: Prerequisite: ENGL 1010 or 1011 or 2011; MCB 2000 or 2210 or 3010.

Grading Basis: Graded

Mechanisms involved in cancer initiation, promotion, and progression: cancer genomes, epigenetic regulation of gene expression and reprogramming, cancer stem cells, alterations in cell signaling networks, cancer cell bioenergetics, environmental exposures and xenobiotic metabolism, development of resistance to therapeutics.

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3843W. Research Literature in Comparative Genomics

3.00 credits

Prerequisites: Prerequisite: ENGL 1010 or 1011 or 2011; MCB 2400 or 2410; open only with consent of instructor. Not open for credit to students who have passed MCB 3841W when offered as "Comparative Genomics."

Grading Basis: Graded

Current research in comparative genomics, which uses cross-species analyses to identify functional genome sequences. Primary research literature concerning the complex and dynamic nature of eukaryotic genomes. Emphasis on communicating scientific findings using experimental data.

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3845W. Microbial Diversity, Ecology and Evolution

3.00 credits

Prerequisites: BIOL 1107; ENGL 1010, ENGL 1011 or ENGL 2011. Recommended preparation: MCB 2610.

Grading Basis: Graded

Readings from the scientific literature will provide a focus for investigating the mechanisms and strategies for the exchange of genetic information, as well as the impact of gene transfer on environmental adaptation and evolution.

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3893. Foreign Study

1.00 - 5.00 credits | May be repeated for credit.

Prerequisites: Open to sophomores or higher.

Grading Basis: Graded

Special topics taken in an international study program. Consent of instructor required, normally to be granted before the student's departure.

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3895. Special Topics

1.00 - 6.00 credits | May be repeated for credit.

Prerequisites: Prerequisites and recommended preparation vary.

Grading Basis: Graded

With a change in content, this course may be repeated for credit.

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3898. Variable Topics

3.00 credits | May be repeated for credit.

Prerequisites: Prerequisites and recommended preparation vary.

Grading Basis: Graded

With a change in topic this course may be repeated for credit.

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3899. Independent Study

1.00 - 6.00 credits | May be repeated for credit.

Prerequisites: None.

Grading Basis: Graded

Designed for the advanced undergraduate student who is pursuing a special problem as an introduction to independent investigation. With a change in topic this course may be repeated for credit.

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3989. Introduction to Research

1.00 - 6.00 credits | May be repeated for credit.

Prerequisites: None.

Grading Basis: Graded

Laboratory research project carried on by the student under the guidance of a faculty member. The student is required to submit a brief report on the research findings at the end of the semester. May be repeated for credit with a change in topic.

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3996W. Research Thesis in Molecular and Cell Biology

3.00 credits

Prerequisites: Three credits of MCB 3989 or 4989, which may be taken concurrently; ENGL 1010 or 1011 or 2011.

Grading Basis: Graded

Writing of a thesis based upon the student's independent laboratory research project.

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4008. Techniques of Biophysical Chemistry

3.00 credits

Prerequisites: MCB 3007 or CHEM 3563 or instructor consent.

Grading Basis: Graded

Theory and applications of biophysical methods for the analysis of the size, shape and interactions of proteins and nucleic acids. Topics include analytical ultracentrifugation, light scattering, X-ray scattering, calorimetry, surface plasmon resonance and single molecule approaches.

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4009. Structure and Function of Biological Macromolecules

3.00 credits

Prerequisites: MCB 2000 or 3010, which may be taken concurrently, or instructor consent.

Grading Basis: Graded

Fundamentals of protein structure and the forces that stabilize structure. Topics include recurrent structural motifs, molecular ancestry/homology, evolution of protein structure, structure-function correlations, and the structural basis of regulation. Discussion of the techniques used to investigate structure, including X-ray diffraction, NMR, TEM, AFM, structure prediction, and computational simulations. Advanced topics may include chaperones, structural genomics and the roles of misfolded proteins in disease.

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4026W. Advanced Biochemistry Laboratory

4.00 credits

Prerequisites: MCB 3010, or MCB 2000 with consent of instructor; ENGL 1010 or 1011 or 2011.

Grading Basis: Graded

Theory and application of modern techniques for separation and characterization of biological macromolecules, including several types of liquid chromatography, liquid scintillation spectro-photometry, and SDS polyacrylamide gel electrophoresis. Instruction in writing a scientific paper.

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4211. Basic Immunology

3.00 credits

Prerequisites: BIOL 1107. Recommended preparation: MCB 2210.

Grading Basis: Graded

An introduction to the genetic, biochemical, and cellular mechanisms of the immune system. This course will address basic aspects of immune function, and will examine abnormal immune function associated with cancer, autoimmune disease, AIDS, and other immunological abnormalities.

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4416. Forensic Application of DNA Science

3.00 credits

Prerequisites: MCB 2400 or 2410

Grading Basis: Graded

DNA analysis in forensic science, with emphasis on molecular genetic technology in criminal investigations and issues surrounding the use of DNA evidence. Team-taught with forensic practitioners.

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4601. Physiology of Archaea and Bacteria

3.00 credits

Prerequisites: MCB 2000, 2610, or 3010. Not open for credit to students who have passed MCB 3601.

Grading Basis: Graded

Examination of biochemical energy generation, regulation of metabolism, and cellular structures of archaea and bacteria. Physiological processes as they occur in nature and the biotechnology industry.

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4624. Experiments in Bacterial Genetics

3.00 credits

Prerequisites: MCB 2610. Recommended preparation: MCB 3617.

Grading Basis: Graded

Experiments in bacterial genetics, emphasizing genetic manipulations and analyses using modern biological techniques including transposon mutagenesis, DNA isolation, PCR, DNA sequencing and phenotypic analysis.

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4893. Foreign Study

1.00 - 5.00 credits | May be repeated for credit.

Prerequisites: Open to sophomores or higher.

Grading Basis: Graded

Special topics taken in an international study program. Consent of program director required, normally to be granted before the student's departure.

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4894. Undergraduate Seminar

1.00 - 6.00 credits | May be repeated for credit.

Prerequisites: None.

Grading Basis: Graded

Credits and hours by arrangement. May be repeated for credit with a change of topic.

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4989. Introduction to Honors Research

1.00 - 6.00 credits | May be repeated for credit.

Prerequisites: Open only to honors students with consent of instructor.

Grading Basis: Honors Credit

Laboratory research project carried on by the student under the guidance of a faculty member. The student is required to submit a brief report on the research findings at the end of the semester. May be repeated for credit with change in topic.

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4997W. Honors Research Thesis in Molecular and Cell Biology

3.00 credits

Prerequisites: Three credits of MCB 3989 or 4989, which may be taken concurrently; ENGL 1010 or 1011 or 2011; open only to honors students.

Grading Basis: Honors Credit

Writing of a thesis based upon a student's independent laboratory research project. SM-2/25/08

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