College of Agriculture and Natural Resources Requirements Admission Bachelor's Degree College University General Education Majors Agriculture and Natural Resources Allied Health Science Animal Science Cytotechnology Diagnostic Genetic Sciences Dietetics Environmental Science Horticulture Individualized Major Landscape Architecture Medical Technology Natural Resources Nutritional Sciences Pathobiology Resource Economics Turfgrass and Soil Science Minors Animal Science Aquaculture Aquaculture Business Management Dairy Management Equine Business Management Food Science Landscape Design Nutrition for Exercise and Sport Ornamental Horticulture Sport Nutrition Therapeutic Horsemanship Education Turfgrass Management Wildlife Conservation Courses Agriculture and Resource Economics (ARE) Agriculture and Natural Resources (AGNR) Allied Health (AH) Animal Science (ANSC) Cytotechnology (CYTO) Diagnostic Genetic Sciences (DGS) Dietetics (DIET) Health Sciences (HESC) Horticulture (HORT) Landscape Architecture (LAND) Medical Technology (MT) Natural Resources Management and Engineering (NRME) Nutritional Sciences (NUSC) Pathobiology and Veterinary Science (PVS) Plant Sciences (PLSC) Soil Science (SOIL) Turfgrass Science (TURF)

 

Diagnostic Genetic Sciences (DGS)

Diagnostic Genetic Sciences Program Director: Martha B. Keagle
Program Office: Room 222, Koons Hall

For major requirements, see the College of Agriculture and Natural Resources, Department of Allied Health Sciences section of this Catalog.
 

3222. Medical Cytogenetics

(222) Both semesters. Four credits. Two 2-hour lectures. Prerequisite: MCB 2000 and 2410 or 2413; all of which may be concurrent. Open to students in the Diagnostic Genetic Sciences Program; others who have met the prerequisites.

Birth defects, prenatal assessment, cell culture and harvest, staining and banding techniques, mechanisms of numerical and structural chromosome abnormality, numerical syndromes, duplication and deletion syndromes, the sex chromosomes, sex chromosome abnormalities, human chromosome nomenclature, mosaicism, genetic imprinting, cancer cytogenetics, molecular cytogenetic testing.

3223. Laboratory in Cytogenetics

(223) Both semesters. Two credits. One 3-hour laboratory period and one 1-hour discussion. Four additional laboratory sessions are required during the first half of the semester. Prerequisite: DGS 3222 which may be taken concurrently. Open only to students enrolled in the Diagnostic Genetic Sciences Program; others with consent of instructor.

Human chromosome morphology and identification, aseptic technique, lymphocyte culture and harvest, chromosome banding, karotyping and microscopic analysis of normal and abnormal cases. A fee of $50 is charged for this course.

3225. Microscopy and Chromosome Imaging

(225) Either semester. One credit. Prerequisite: DGS 3223 which may be taken concurrently. Open only to students enrolled in the Diagnostic Genetics Sciences Program; others with consent of instructor.

Theory and techniques of brightfield and fluorescence microscopy, and computerized chromosome imaging.

3226. Current Genetic Research

(226) Either semester. Variable credits. Prerequisite: DGS 3222 or MCB 2410 or MCB 2413; instructor consent. May be repeated one time for credit.

Retrieval, review and discussion of current primary genetics literature in addition to attending and reviewing University research seminars/guest speakers.

3999. Independent Study for Undergraduates

(299) Either semester. Credits and hours by arrangement. Open only with consent of instructor. May be repeated for credit.

This course is designed primarily for students who wish to extend their knowledge in some specialized area in the field of diagnostic genetic sciences.

4095. Special Topics

(298) Either semester. Credits and hours by arrangement. Open only with consent of instructor. May be repeated for credit.

Application of the scientific method of inquiry to planning, implementation, evaluating and reporting a study of a problem in cytogenetics.

4224. Cancer Cytogenetics

(224) Offered summer.  Two credits.  Prerequisite: DGS 3223.  Open only to students enrolled in the Diagnostic Genetic Sciences Program; others with consent of instructor.

Chromosome instability syndromes, genetic basis of cancer, cytogenetics of solid tumors and hematologic malignancies, and nomenclature of acquired changes.

4234. Diagnostic Molecular Technologies

(234) Both semesters. Three credits. Prerequisite: MCB 2410 or 2413; and MLS 3121 or MCB 3212 which may be taken concurrently. Open only to students enrolled in the Diagnostic Genetic Sciences Program.

DNA and RNA diagnostic technologies used in clinical settings; clinical applications in prenatal diagnosis; cancer management, transplantation, paternity testing, forensic medicine and microbiology. Others with instructor consent.

4234W. Diagnostic Molecular Technologies

(234W) Prerequisite: MCB 2410 or 2413; and MLS 3121 or MCB 3212 which may be taken concurrently; ENGL 1010 or 1011 or 3800. Open only to students enrolled in the Diagnostic Genetic Sciences Program.

4235. Laboratory in Molecular Diagnostics

(235) Both semesters. Two credits. Prerequisite: DGS 4234 which may be taken concurrently. Open only to students enrolled in the Diagnostic Genetic Sciences Program.

DNA isolation, blotting techniques, fluorescent in situ hybridization, polymerase chain reaction and Genprobe assay. A fee of $50 is charged for this course.

4246. Contemporary Issues in Human Genetics

(246) Both semesters. Three credits. Prerequisite: DGS 3223. Open only to students enrolled in the Diagnostic Genetic Sciences Program; others with consent of the instructor.

Advanced karotyping and microscopic diagnosis; report writing; historical perspective; recent advances and future trends in human genetics; ethical issues of genetic research, technological advances, genetic diagnosis and the practice of medical genetics; exploration of the lay person's understanding of human genetics and genetic diagnosis.

4501. Specimen Processing

(250) Both semesters. Two credits. Prerequisite: In order to enroll in this course, a student must have earned a "C" or better in DGS 4234 and 4235. Open to DGS molecular students only.

Theory and methods for processing and evaluating specimens for nucleic acid isolation.

4502. Nucleic Acid Isolation

(251) Both semesters. Four credits. Prerequisite: In order to enroll in this course, a student must have earned a "C" or better in DGS 4234 and 4235. Open to DGS molecular students only.

Isolation, manipulation and evaluation of nucleic acids.

4503. Amplification Methods

(261) Both semesters. Six credits. Prerequisite: In order to enroll in this course, a student must have earned a "C" or better in DGS 4234 and 4235. Open only to DGS molecular students only.

Practicum experience in DNA and/or RNA amplification stressing polymerase chain reaction.

4510. In Situ Hybridization Methods

(275) Both semesters. Two credits. Prerequisites: In order to enroll in this course, a student must have earned a "C" or better in DGS 4234 and 4235. Open to DGS molecular students only.

Practicum in fluorescence in situ hybridization or other in situ hybridization techniques.

4511. Topics in Molecular Genetics

(276) Both semesters. Two credits. Prerequisite: In order to enroll in this course, a student must have earned a "C" or better in DGS 4234 and 4235. Open to DGS molecular students only.

Exploration of an individual area of interest in molecular genetics.

4512. Cloning Techniques

(252) Both semesters. Two credits. Prerequisite: In order to enroll in this course, a student must have earned a "C" or better in DGS 4234 and 4235. Open to DGS molecular students only.

Theory and techniques of cloning.

4513. Blotting Applications

(253) Both semesters. Two credits. Prerequisite: In order to enroll in this course, a student must have earned a "C" or better in DGS 4234 and 4235. Open to DGS molecular students only.

Theory and techniques of nucleic acid and/or protein blotting (e.g. Southern blot, reverse clot blot).

4514. DNA Sequencing

(278) Both semesters. Two credits. Prerequisite:In order to enroll in this course, a student must have earned a "C" or better in DGS 4234 and 4235.Open to DGS molecular students only.

Practicum experience in DNA sequencing.

4515. Microbiological Applications of Molecular Diagnostics

(279) Both semesters. Two credits. Prerequisite: In order to enroll in this course, a student must have earned a "C" or better in DGS 4234 and 4235. Open only to students enrolled in the Molecular Diagnostic Sciences Program; others with consent of the instructor.

Practicum experience in the application of molecular technologies to microbiology.

4550. Research in Molecular Genetics

(273) Both semesters. One credit. Prerequisites: In order to enroll in this course, a student must have earned a "C" or better in AH 4241W, DGS 4234 and 4235. Open only to DGS molecular students only.

Design and implementation of a research project in molecular genetics.

4650. DNA Technology in Forensic Science

(289) Either semester. Credits and hours by arrangement. Prerequisite: To enroll in this course, the student must have earned a "C" or better in DGS 4503 and 4550. Open only to Diagnostic Genetic Sciences molecular diagnostic sciences certificate students. Brown

Practicum experience with forensic applications of DNA testing

4701. Peripheral Blood Cytogenetics

(281) Both semesters. Four credits. Prerequisite: In order to enroll in this course, the student must have earned a "C" or better in DGS 3222 and DGS 3223. Open only to Diagnostic Genetic Sciences majors. 

Culture, harvest, banding and analysis of peripheral blood samples.

4702. Prenatal Cytogenetics

(286) Both semesters. Four credits. Prerequisite: In order to enroll in this course, the student must have earned a "C" or better in DGS 3222 and DGS 3223. Open only to Diagnostic Genetic Sciences majors. 

Culture, harvest, banding and analysis of amniotic fluids, products of conception, and other fetal samples

4703. Bone Marrow Cytogenetics

(280) Both semesters. Four credits. Prerequisite: In order to enroll in the course, the student must have earned a "C" or better in DGS 3222, DGS 3223 and DGS 4224. Open only to Diagnostic Genetic Sciences majors. 

Culture, harvest, banding and analysis of leukemic bone marrow samples; chromosomal abnormalities associated with hematologic malignancies.

4712. Fluorescence in situ Hybridization

(265) Both semesters. Two credits. Prerequisite: In order to enroll in this course, a student must have earned a grade of C or better in DGS 3222, 4234 and 4235. Open only to DGS students in the Cytogenetics Concentration.

Designed to give the student hands-on experience with Fluorescense in situ Hybridization.

4713. Practicum in Imaging and Staining

(266) Both semesters. One credit. Prerequisite: In order to enroll in this course, a grade of C or better in DGS 3222 and 3223. Open only to DGS students in the Cytogenetics Concentration.

Designed to give the student hands-on experience in chromosome imaging and routine and special cytogenetic staining techniques

4750. Research in Cytogenetics

(285) Both semesters. One credit. Prerequisite: In order to enroll in this course, the student must have earned a "C" or better in AH 4241W,  DGS 3222 and 3223. Open only to Diagnostic Genetic Sciences majors. 

Design and implementation of a research project in clinical cytogenetics.

.4997. Honors Research

(290) Either semester. Three credits. Open only to Diagnostic Genetic Sciences Honors students. 

Design and implementation of an honors research project.